Browsing: Gut Health & Microbiome

Research in microbiome science has increasingly highlighted the fundamental impact of the gut microbiota on human health, with implications ranging from metabolic regulation to immune function and even neurobehavioral outcomes. Historically, most studies have concentrated on broad correlations between microbial populations and host health or disease, classifying individuals based on generalized community structures or typical…

Researchers at UC Davis School of Medicine have uncovered how an imbalanced gut microbiome escalates the production of metabolic byproducts by certain gut bacteria. This imbalance drives a feedback loop that worsens chronic kidney disease (CKD) in mice. The scientists identified an investigational drug that might break the destructive cycle. The findings were published in Science

The mammalian gut teems with microbes that interact with each other dynamically to maintain the host’s health. An imbalance, or dysbiosis, in the gut microbiome is linked to diseases ranging from metabolic disorders to cancers.1However, a majority of gut microbiome dysbiosis research focuses only on identifying bacterial taxa that differ between healthy and diseased states,…